This Working Group is interested in the mechanistic studies of FeS cluster biogenesis using biochemical, biophysical, spectroscopic and structural approaches. Understand at a molecular level how iron, sulfur, electrons and protein dynamics work together to assemble an FeS cluster and transfer it to cellular target is fully exciting. The projects concerned are the FeS cluster assembly systems from E. coli (model) and from pathogens and the machineries involved in FeS assembly and transfer in eukaryotes during immune response to pathogens.